Friday, October 5, 2018

What tests do you need to do for tuberculosis? What are the treatments for tuberculosis?

What tests do you need to do for tuberculosis? What are the treatments for tuberculosis?
What tests do you need to do for tuberculosis? What are the treatments for tuberculosis?
An examination
1. Smear test
The sputum of the patient's sputum or other parts of the body is made into a smear to detect the patient's yin and positive under the microscope.

2. X-ray inspection
Not only can tuberculosis be detected early, but the location, extent, nature, development and effects of the lesion can be diagnosed.

3. Tuberculin test
(1) Positive indicates tuberculosis infection, but not necessarily diseased. A dilution of the skin test is positive, often suggesting active tuberculosis in the body.
(2) Negative Indicates that there is no tuberculosis infection. However, the following situations should still be excluded.

  • After tuberculosis infection, it takes 4-8 weeks for allergic reaction to be fully established; therefore, in the early stage of allergic reaction, the lignin test can be negative.
  • The use of immunosuppressive agents such as glucocorticoids, malnutrition, and patients with measles and whooping cough can temporarily disappear.
  • Severe tuberculosis and various critically ill patients do not respond to sputum.
  • Others: The sputum response of patients with lymphoid immune system defects (leukemia, sarcoidosis) and the elderly is also often negative.




4. Lymphocyte culture + gamma interferon release test
It is more sensitive and specific than the tuberculin test (PPD) skin test, and is not affected by previous BCG injection, but it cannot distinguish between latent infection or active tuberculosis.

5. Molecular biology methods PCR-TB.

Treatment
Before determining treatment principles and selecting treatments, determine the type of tuberculosis and current stage of disease progression and good condition, and check for the presence of active tuberculosis elsewhere in the lung. Also follow the following treatment principles:

1. There are many bacteria in the early lesions, and the drugs are easy to function;

2. The dosage is suitable to exert the maximum bactericidal or bacteriostatic effect, and the patient is also tolerant, and the toxicity is not large;

3. Combination therapy can prevent drug resistance, and the combination drug can also select drugs for various metabolic state bacteria and intracellular and extracellular bacteria, and has achieved the purpose of enhancing drug efficacy;

4. The medication can not be interrupted arbitrarily. Intermittent therapy has specific requirements in terms of dose and interval. The usage also has certain regularity and is not intermittent therapy.

5. Chemotherapy should adhere to the whole process, the purpose is to eliminate the holding bacteria and prevent recurrence, the whole process is not necessarily long-term.
Only by following the above five principles, early, appropriate, joint, regular, and full course can we ensure complete treatment.

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